Ultrasound PECS 2 Versus Dexmedetomidine Infusion for Pain Management after Radical Mastectomy

Background: Pectoralis-Serratus interfascial plane block is a peripheral of the thoracic wall that presents analgesia its anterolateral portion. Dexmedetomidine, specific α-2 adrenoceptor agonist, has sedative, anxiolytic, and analgesic properties. The aim this work was to assess safety efficacy in contrast with dexmedetomidine infusion for unilateral radical mastectomy.
 Methods: This prospective randomized study carried out on 60 adult patients American Society Anaesthesiologists (ASA) physical status I/II scheduled elective mastectomy. cases were classified randomly into two equal groups: group I: received ultrasound guided pectoralis serratus interfacial II: infusion. All subjected routine laboratory investigations (coagulation profile, CBC, liver renal function tests) visual analogue scale (VAS).
 Results: Total amount fentanyl increments, Ramsey sedation score total (morphine) consumption 1st 24 hours postoperative significantly decreased I contrasted II (P<0.001). Time first rescue increased than (P <0.001). Bradycardia considerably = 0.026). VAS at rest exercise 1, 2, 4 6 (P<0.05).
 Conclusions: PECS-II blocks are superior provide adequate post-operative (lower analgesia) hemodynamic stability. less complications.